JJKK 048
Product Sizes
25 mg
£ POA
HY-108613-25MG
5 mg
£ POA
HY-108613-5MG
100 mg
£ POA
HY-108613-100MG
10 mg
£ POA
HY-108613-10MG
50 mg
£ POA
HY-108613-50MG
10mM/1mL
£ POA
HY-108613-10MM
About this Product
- SKU:
- HY-108613
- CAS Number:
- 1515855-97-6
- Extra Details:
- JJKK 048 is a highly selective and potent monoacylglycerol lipase (MAGL) inhibitor with IC50 values of 214 pM; 275 pM and 363 pM for human; rat; and mouse MAGL. JJKK 048 displays low cross-reactivity with other endocannabinoid targets. JJKK 048 can be used in the research of diseases such as cancer; neurodegenerative diseases; and pain[1][2].
- Molecular Weight:
- 434.44
- Purity:
- 99.55
- References:
- [1]Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72.|[2]Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90.
- Research Area:
- Cancer; Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
