(E)-FeCP-oxindole
Product Sizes
1 mg
£ POA
HY-108444A-1MG
About this Product
- SKU:
- HY-108444A
- CAS Number:
- 884338-18-5
- Extra Details:
- (Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity; acting on B16 murine melanoma lines with IC50 less than 1 μM[1].
- Molecular Weight:
- 329.17
- References:
- [1]John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Protein Tyrosine Kinase/RTK
