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Proteins and Peptides

(Z)-FeCP-oxindole

Product Sizes
10 mg
£ POA
HY-108444-10MG
5 mg
£ POA
HY-108444-5MG
100 mg
£ POA
HY-108444-100MG
25 mg
£ POA
HY-108444-25MG
50 mg
£ POA
HY-108444-50MG
10mM/1mL
£ POA
HY-108444-10MM
About this Product
SKU:
HY-108444
CAS Number:
1137967-28-2
Extra Details:
(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity; acting on B16 murine melanoma lines with IC50 less than 1 μM[1].
Molecular Weight:
329.17
Purity:
99.62
References:
[1]John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Protein Tyrosine Kinase/RTK
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