CPT2
Product Sizes
50 μg
£ POA
HY-108433-50UG
About this Product
- SKU:
- HY-108433
- Additional Names:
- Carnitine palmitoyltransferase 2
- Application:
- Immunoprecipitation
- CAS Number:
- 1670277-66-3
- Extra Details:
- CPT2 (Carnitine palmitoyltransferase 2); an enzyme that participates in fatty acid oxidation; also is a colorectal cancer (CRC) prognostic biomarker. CPT2 overexpression can activate p-p53 to increase p53 expression; thereby inhibiting tumor proliferation and promoting apoptosis. CPT2 deficiency results in the most common inherited disorder of long-chain fatty acid oxidation affecting skeletal muscle. Downregulation of CPT2 is also highly correlated with the progression of various cancers and has potential for cancer research[1][2].
- References:
- [1]Liu F, et al. Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer. Cell Signal. 2022 Apr;92:110267. |[2]Joshi PR, et al. Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach. Molecules. 2020 Apr 13;25(8):1784.
- Research Area:
- Cancer; Metabolic Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
