(Rac)-AMG8379
Product Sizes
10 mg
£ POA
HY-108425B-10MG
1 mg
£ POA
HY-108425B-1MG
5 mg
£ POA
HY-108425B-5MG
About this Product
- SKU:
- HY-108425B
- Additional Names:
- (Rac)-AMG8380
- CAS Number:
- 1641574-26-6
- Extra Details:
- (Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent; orally active and selective sulfonamide antagonist of NaV1.7; with IC50s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7; respectively [1].
- Molecular Weight:
- 543.93
- Purity:
- 99.25
- References:
- [1]Kornecook TJ, et al. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7. J Pharmacol Exp Ther. 2017 Jul;362(1):146-160.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel
