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Proteins and Peptides

(Rac)-Lanicemine

Product Sizes
50 mg
£ POA
HY-108235B-50MG
5 mg
£ POA
HY-108235B-5MG
10 mg
£ POA
HY-108235B-10MG
10mM/1mL
£ POA
HY-108235B-10MM
25 mg
£ POA
HY-108235B-25MG
About this Product
SKU:
HY-108235B
Additional Names:
(Rac)-AZD6765
CAS Number:
61890-25-3
Extra Details:
(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells; respectively). Antidepressant effects[1].
Molecular Weight:
198.27
Purity:
99.63
References:
[1]Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.
Research Area:
Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Membrane Transporter/Ion Channel;Neuronal Signaling
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