(Rac)-ALX 5407
Product Sizes
10 mg
£ POA
HY-107526-10MG
About this Product
- SKU:
- HY-107526
- Additional Names:
- (Rac)-NFPS
- CAS Number:
- 405225-21-0
- Extra Details:
- NFPS is a selective; non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1; respectively[1]. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion[2].
- Molecular Weight:
- 393.45
- References:
- [1]Mallorga PJ, et al. Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine. Neuropharmacology. 2003 Oct;45(5):585-93.|[2]Huang B, et al. GlyT1 Inhibitor NFPS Exerts Neuroprotection via GlyR Alpha1 Subunit in the Rat Model of Transient Focal Cerebral Ischaemia and Reperfusion. Cell Physiol Biochem. 2016;38(5):1952-62.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel;Neuronal Signaling
