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Proteins and Peptides

(3aS;4R;9bR)-G-1

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HY-107216A-1EACH
About this Product
SKU:
HY-107216A
CAS Number:
925419-53-0
Extra Details:
(3aS;4R;9bR)-G-1 is a highly selective G protein-coupled receptor GPR30 (GPER) agonist with a Ki value of approximately 7 nM. (3aS;4R;9bR)-G-1 activates rapid signaling pathways such as intracellular calcium mobilization and PI3K signaling through GPR30; promoting uterine epithelial cell proliferation and exerting antidepressant effects. (3aS;4R;9bR)-G-1 is promising for research of breast cancer and depression[1].
Molecular Weight:
412.28
References:
[1]Dennis MK, et al. In vivo effects of a GPR30 antagonist. Nat Chem Biol. 2009 Jun;5(6):421-7.
Research Area:
Cancer; Neurological Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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