(rel)-MK 287
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HY-106899A-1EACH
About this Product
- SKU:
- HY-106899A
- Additional Names:
- (rel)-L-680573
- CAS Number:
- 143445-03-8
- Extra Details:
- (rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent; selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet; polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1; 3.2; and 5.49 nM; respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56; 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease; such as thrombosis[1].
- Molecular Weight:
- 510.60
- References:
- [1]S B Hwang, et al. MK 287: a potent, specific, and orally active receptor antagonist of platelet-activating factor. J Lipid Mediat. 1993 Jun;7(2):115-34.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
