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Proteins and Peptides

(E)-Ajoene

Product Sizes
1 mg (42.66 mM * 100 μL in Ethyl acetate)
£ POA
HY-106784A-1MG
About this Product
SKU:
HY-106784A
CAS Number:
92284-99-6
Extra Details:
(E)-Ajoene is a oxygenated ajoene and organosulfur compound; which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region[1][2].
Molecular Weight:
234.40
Purity:
95
References:
[1]Rakshit D, et al. The Pharmacological Activity of Garlic (Allium sativum) in Parkinson's Disease: From Molecular Mechanisms to the Therapeutic Potential. ACS Chem Neurosci. 2023 Mar 15;14(6):1033-1044. |[2]Yoo DY, et al. Neuroprotective effects of Z-ajoene, an organosulfur compound derived from oil-macerated garlic, in the gerbil hippocampal CA1 region after transient forebrain ischemia. Food Chem Toxicol. 2014 Oct;72:1-7.
Research Area:
Neurological Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Solution; -20[o]C; 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Anti-infection;Apoptosis
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