AH 6809
Product Sizes
5 mg
£ POA
HY-10418-5MG
100 mg
£ POA
HY-10418-100MG
10 mg
£ POA
HY-10418-10MG
50 mg
£ POA
HY-10418-50MG
10mM/1mL
£ POA
HY-10418-10MM
25 mg
£ POA
HY-10418-25MG
About this Product
- SKU:
- HY-10418
- CAS Number:
- 33458-93-4
- Extra Details:
- AH 6809 is an antagonist of EP and DP receptor; with Kis of 1217; 1150; 1597; and 1415 nM for the cloned human EP1; EP2; EP3-III; and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor[1][2][3].
- Molecular Weight:
- 298.29
- Purity:
- 99.57
- References:
- [1]Abramovitz M, et, al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta. 2000 Jan 17;1483(2):285-93.|[2]Kiriyama M, et, al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.|[3]Woodward DF, et, al. 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist. Biochem Pharmacol. 1995 Nov 9;50(10):1731-3.|[4]Zoccal KF, et, al. Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality. Nat Commun. 2016 Feb 23;7:10760.|[5]Keery RJ, et, al. AH6809, a prostaglandin DP-receptor blocking drug on human platelets. Br J Pharmacol. 1988 Jul;94(3):745-54.
- Research Area:
- Inflammation/Immunology; Endocrinology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein
