IRL 2500
Product Sizes
50 mg
£ POA
HY-103460-50MG
100 mg
£ POA
HY-103460-100MG
1 mg
£ POA
HY-103460-1MG
10 mg
£ POA
HY-103460-10MG
5 mg
£ POA
HY-103460-5MG
25 mg
£ POA
HY-103460-25MG
10mM/1mL
£ POA
HY-103460-10MM
About this Product
- SKU:
- HY-103460
- CAS Number:
- 169545-27-1
- Extra Details:
- IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors; respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo[1].
- Molecular Weight:
- 573.68
- Purity:
- 99.27
- References:
- [1]Balwierczak JL, et al. Characterization of a potent and selective endothelin-B receptor antagonist, IRL 2500.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S393-6.|[2]Webb RL, et al. Effects of the ETB-selective antagonist IRL 2500 in conscious spontaneously hypertensive and Wistar-Kyoto rats.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S389-92.
- Research Area:
- Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein
