Lys-[Des-Arg9]Bradykinin
Product Sizes
1 mg
£ POA
HY-103295-1MG
About this Product
- SKU:
- HY-103295
- Application:
- Electron Microscopy
- CAS Number:
- 71800-36-7
- Extra Details:
- Lys-[Des-Arg9]Bradykinin; a naturally occurring kinin; is a potent and highly selective bradykinin B1 receptor agonist with a Ki of 0.12 nM; 1.7 nM and 0.23 nM for human; mouse and rabbit B1 receptors; respectively. Lys-[Des-Arg9]Bradykinin has low inhibitory activity on B2 receptors[1][2].
- Molecular Weight:
- 1032.20
- References:
- [1]Rosalind Gulliver, et al. Lys-des[Arg9]-bradykinin alters migration and production of interleukin-12 in monocyte-derived dendritic cells. Am J Respir Cell Mol Biol. 2011 Sep;45(3):542-9.|[2]L M Fredrik Leeb-Lundberg, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.|[3]G Drapeau, et al. Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins. J Pharmacol Exp Ther. 1991 Dec;259(3):997-1003.
- Research Area:
- Metabolic Disease; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
