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Proteins and Peptides

(±)-Enitociclib (Standard)

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HY-103019AR-1EACH
About this Product
SKU:
HY-103019AR
CAS Number:
1610358-53-6
Extra Details:
(±)-Enitociclib (Standard) is the analytical standard of (±)-Enitociclib (HY-103019A). This product is intended for research and analytical applications. (±)-Enitociclib ((±)-BAY-1251152) is the racemic mixture of Enitociclib (HY-103019E). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II; thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells; and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003); and can be used in the research of hematological malignancies[1][2].
Molecular Weight:
404.43
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules