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Proteins and Peptides

(+)-N-Allylnormetazocine (hydrochloride)

Product Sizes
5 mg
£ POA
HY-101376-5MG
About this Product
SKU:
HY-101376
Additional Names:
(+)-SKF 10047 (hydrochloride); (+)-N-Allyl-N-normetazocine (hydrochloride)
CAS Number:
133005-41-1
Extra Details:
(+)-N-Allylnormetazocine ((+)-SKF 10047) hydrochloride is a benzomorphan opioid with psychotomi metic effects. (+)-N-Allylnormetazocine hydrochloride is an opioid receptor antagonist with Ki values of 300 nM and 27 μM for σ1 and σ2 opioid receptors; respectively. (+)-N-Allylnormetazocine hydrochloride can be used for the research of neurological disease[1][2].
Molecular Weight:
293.83
Purity:
99.6
References:
[1]May EL, et al. Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues. J Med Chem. 2000 Dec 28;43(26):5030-6.|[2]Brady KT, et al. Stereoisomers of N-allylnormetazocine: phencyclidine-like behavioral effects in squirrel monkeys and rats. Science. 1982 Jan 8;215(4529):178-80.
Research Area:
Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; stored under nitrogen; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Neuronal Signaling
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