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Proteins and Peptides

(Rac)-VU 6008667

Product Sizes
25 mg
£ POA
HY-101281A-25MG
50 mg
£ POA
HY-101281A-50MG
5 mg
£ POA
HY-101281A-5MG
1 mg
£ POA
HY-101281A-1MG
10 mg
£ POA
HY-101281A-10MG
About this Product
SKU:
HY-101281A
CAS Number:
2092917-63-8
Extra Details:
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM; pIC50= 5.75); has high CNS penetration[1].
Molecular Weight:
438.85
Purity:
99.85
References:
[1]McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.
Research Area:
Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Neuronal Signaling
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