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Proteins and Peptides

Milademetan (tosylate)

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HY-101266A-1EACH
About this Product
SKU:
HY-101266A
Additional Names:
DS-3032 (tosylate)
Application:
Antibody Microarray
CAS Number:
1398569-75-9
Extra Details:
Milademetan tosylate is the tosylate salt form of Milademetan (HY-101266). Milademetan tosylate is an orally active inhibitor for MDM2. Milademetan tosylate arrests the cell cycle at G1 pahse; induces the apoptosis Milademetan tosylate restores the p53 activity by targeting the p53-MDM2 interaction; and exhibits anticancer activity against Merkel cell carcinoma (MCC)[1].
Molecular Weight:
790.73
References:
[1]Ananthapadmanabhan V, et al., Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma. JCI Insight. 2022 Jul 8;7(13):e160513.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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