(S)-Monastrol
Product Sizes
1 mg
£ POA
HY-101071-1MG
About this Product
- SKU:
- HY-101071
- Additional Names:
- (+)-Monastrol
- Application:
- Antibody Microarray
- CAS Number:
- 254753-54-3
- Extra Details:
- (S)-Monastrol ((+)-Monastrol) is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cancer cell lines. (S)-Monastrol arrests mammalian cells in mitosis with monopolar spindles[1][2].
- Molecular Weight:
- 292.35
- References:
- [1]Marques LA, et al. Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells. Naunyn Schmiedebergs Arch Pharmacol. 2016 Dec;389(12):1279-1288.|[2]Mayer TU, et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science. 1999 Oct 29;286(5441):971-4.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Cytoskeleton
