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Proteins and Peptides

(E)-3-AP

Product Sizes
25 mg
£ POA
HY-10082A-25MG
10 mg
£ POA
HY-10082A-10MG
About this Product
SKU:
HY-10082A
Additional Names:
(E)-PAN-811; (E)-NSC# 663249; (E)-OCX191
Application:
Antibody Microarray
CAS Number:
200933-27-3
Extra Details:
(E)-3-AP is the E configuration of 3-AP. 3-AP is a potent ribonucleotide reductase inhibitor. 3-AP shows anti-proliferative activity. 3-AP shows anticancer activity in L1210 leukemia model. 3-AP inhibits RR activity and DNA synthesis[1][2].
Molecular Weight:
195.24
Purity:
99.24
References:
[1]Finch RA, et al. Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity. Adv Enzyme Regul. 1999;39:3-12. |[2]Enyedy ÉA ,et al. Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation. Dalton Trans. 2020 Dec 8;49(46):16887-16902.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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