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Proteins and Peptides

(1α;1'S;4β)-Lanabecestat

Product Sizes
50 mg
£ POA
HY-100740C-50MG
10 mg
£ POA
HY-100740C-10MG
5 mg
£ POA
HY-100740C-5MG
100 mg
£ POA
HY-100740C-100MG
10mM/1mL
£ POA
HY-100740C-10MM
25 mg
£ POA
HY-100740C-25MG
250 mg
£ POA
HY-100740C-250MG
500 mg
£ POA
HY-100740C-500MG
About this Product
SKU:
HY-100740C
Additional Names:
(1α;1'S;4β)-AZD3293; (1α;1'S;4β)-LY3314814
CAS Number:
1384082-96-5
Extra Details:
(1α;1'S;4β)-Lanabecestat ((1α;1'S;4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent; orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM[1].
Molecular Weight:
412.53
Purity:
96.01
References:
[1]Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23.
Research Area:
Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Neuronal Signaling
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