(S)-GSK-F1
Product Sizes
50 mg
£ POA
HY-100603A-50MG
25 mg
£ POA
HY-100603A-25MG
10 mg
£ POA
HY-100603A-10MG
5 mg
£ POA
HY-100603A-5MG
1 mg
£ POA
HY-100603A-1MG
About this Product
- SKU:
- HY-100603A
- CAS Number:
- 1384097-27-1
- Extra Details:
- (S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα). (S)-GSK-F1 inhibits PI4Kα; PI4Kβ; PI4Kγ; PI3Kα; PI3Kβ and PI3Kδ with pIC50 of 8.3; 6.0; 5.6; 5.6; 5.1 and 5.6; respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model[1].
- Molecular Weight:
- 603.52
- Purity:
- 98.01
- References:
- [1]Leivers AL, et al., Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents. J Med Chem. 2014 Mar 13;57(5):2091-106.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- PI3K/Akt/mTOR
