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Proteins and Peptides

(S)-Crizotinib (Standard)

Product Sizes
100 mg
£ POA
HY-100549R-100MG
10 mg
£ POA
HY-100549R-10MG
5 mg
£ POA
HY-100549R-5MG
50 mg
£ POA
HY-100549R-50MG
25 mg
£ POA
HY-100549R-25MG
About this Product
SKU:
HY-100549R
CAS Number:
1374356-45-2
Extra Details:
(S)-Crizotinib (Standard) is the analytical standard of (S)-Crizotinib (HY-100549). This product is intended for research and analytical applications. (S)-Crizotinib is a potent and selective MTH1 (mutT homologue) inhibitor with an IC50 of 330 nM. (S)-Crizotinib disrupts nucleotide pool homeostasis via MTH1 inhibition; induces an increase in DNA single strand breaks; activates DNA repair in human colon carcinoma cells; and effectively suppresses tumour growth in animal models[1].
Molecular Weight:
450.34
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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