NPS-1034
Product Sizes
10 mg
£ POA
HY-100509-10MG
100 mg
£ POA
HY-100509-100MG
25 mg
£ POA
HY-100509-25MG
5 mg
£ POA
HY-100509-5MG
50 mg
£ POA
HY-100509-50MG
10mM/1mL
£ POA
HY-100509-10MM
About this Product
- SKU:
- HY-100509
- CAS Number:
- 1221713-92-3
- Extra Details:
- NPS-1034 is a dual inhibitor of AXL and MET with IC50s of 10.3 and 48 nM; respectively.
- Molecular Weight:
- 551.54
- Purity:
- 98.0
- References:
- [1]Rho JK, et al. MET and AXL inhibitor NPS-1034 exerts efficacy against lung cancer cells resistant to EGFR kinase inhibitors because of MET or AXL activation. Cancer Res. 2014 Jan 1;74(1):253-62.|[2]Shin JS, et al. NPS-1034, a novel MET inhibitor, inhibits the activated MET receptor and its constitutively active mutants. Invest New Drugs. 2014 Jun;32(3):389-99.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Protein Tyrosine Kinase/RTK
