(Rac)-SCH 563705
Product Sizes
100 mg
£ POA
HY-10011B-100MG
50 mg
£ POA
HY-10011B-50MG
25 mg
£ POA
HY-10011B-25MG
10 mg
£ POA
HY-10011B-10MG
5 mg
£ POA
HY-10011B-5MG
About this Product
- SKU:
- HY-10011B
- CAS Number:
- 2701435-64-3
- Extra Details:
- (Rac)-SCH 563705 is a racemic mixture of SCH 563705 (HY-10011). SCH 563705 (compound 16) is a potent and orally active CXCR2 and CXCR1 antagonist with IC50 values of 1.3 nM and 7.3 nM and Ki values of 1 nM and 3 nM; respectively[1][2].
- Molecular Weight:
- 425.48
- Purity:
- 99.78
- References:
- [1]Min S H, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis[J]. Biochemical and biophysical research communications, 2010, 391(1): 1080-1086.|[2]Chao J, et al. C (4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists[J]. Bioorganic & medicinal chemistry letters, 2007, 17(13): 3778-3783.
- Research Area:
- Endocrinology; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation
