(S)-SCH 563705
Product Sizes
25 mg
£ POA
HY-10011A-25MG
5 mg
£ POA
HY-10011A-5MG
50 mg
£ POA
HY-10011A-50MG
100 mg
£ POA
HY-10011A-100MG
10 mg
£ POA
HY-10011A-10MG
About this Product
- SKU:
- HY-10011A
- Application:
- Electron Microscopy
- Extra Details:
- (S)-SCH 563705 is a S-enantiomer of SCH 563705. SCH 563705 (compound 16) is a potent and orally available CXCR2 and CXCR1 antagonist; with IC50s of 1.3 nM; 7.3 nM and Kis of 1 and 3 nM; respectively[1][2].
- Molecular Weight:
- 425.48
- Purity:
- 99.94
- References:
- [1]Min SH, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis. Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6.|[2]Chao J, et al. C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3778-83.
- Research Area:
- Endocrinology; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation
