Flavopiridol (Hydrochloride)
Product Sizes
100 mg
£ POA
HY-10006-100MG
5 mg
£ POA
HY-10006-5MG
50 mg
£ POA
HY-10006-50MG
10 mg
£ POA
HY-10006-10MG
25 mg
£ POA
HY-10006-25MG
500 mg
£ POA
HY-10006-500MG
10mM/1mL
£ POA
HY-10006-10MM
About this Product
- SKU:
- HY-10006
- Additional Names:
- Alvocidib (Hydrochloride); L86-8275 (Hydrochloride); HMR-1275 (Hydrochloride)
- CAS Number:
- 131740-09-5
- Extra Details:
- Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK; competing with ATP to inhibit CDKs including CDK1; CDK2; CDK4 with IC50s of 30; 170; 100 nM; respectively.
- Molecular Weight:
- 438.30
- Purity:
- 99.73
- References:
- [1]Mahoney E, et al. ER stress and autophagy: new discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol.Blood. 2012 Aug 9;120(6):1262-1273.|[2]Keskin H, et al. Complex effects of flavopiridol on the expression of primary response genes. Cell Div. 2012 Mar 29;7:11.|[3]Kim KS, et al.Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects. J Med Chem. 2000 Nov 2;43(22):4126-34.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Autophagy;Cell Cycle/DNA Damage
