Human CDA / Cytidine Deaminase Protein (Recombinant His)
Product Sizes
100 ug
£ POA
LS-G961-100UG
20 ug
£ POA
LS-G961-20UG
500 ug
£ POA
LS-G961-500UG
About this Product
- SKU:
- LS-G961
- Additional Names:
- CDA, Cytidine aminohydrolase, Cytidine deaminase, Small cytidine deaminase, CDD, Cytosine nucleoside deaminase
- Buffer:
- 20 mM Tris-HCl, pH 8.0, 100 mM NaCl, 2 mM EDTA, 1 mM DTT, 40% Glycerol
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2-deoxycytidine for uMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Purity:
- >90%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:961
