Mouse IL-33 Protein (Recombinant His)

Product Sizes

10 ug

£ POA

LS-G3081-10UG

100 ug

£ POA

LS-G3081-100UG

20 ug

£ POA

LS-G3081-20UG

250 ug

£ POA

LS-G3081-250UG

50 ug

£ POA

LS-G3081-50UG

500 ug

£ POA

LS-G3081-500UG

About this Product

SKU:: LS-G3081
Additional Names:: IL33, C9orf26, DVS27, DVS27-related protein, IL-1F11, IL-33, Interleukin-33, NFEHEV, NF-HEV, Interleukin-1 family member 11, NFHEV, IL1F11, Interleukin 33, RP11-575C20.2
Buffer:: Phosphate buffer saline,10% glycerol, 1mM DTT.
Concentration:: 0.5 mg/ml
Extra Details:: Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Recombinant mouse IL33 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Purity:: >85%
Shipping Conditions:: Blue Ice
Storage Conditions:: 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: LifeSpan Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins

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