Human HLA-DRB1 Protein (Recombinant His)
Product Sizes
100 ug
£ POA
LS-G2798-100UG
20 ug
£ POA
LS-G2798-20UG
500 ug
£ POA
LS-G2798-500UG
About this Product
- SKU:
- LS-G2798
- Additional Names:
- HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, Human leucocyte antigen DRB1, MHC class II antigen DRB1*10, MHC class II antigen, MHC class II antigen DRB1*1, HLA-DRB2, Lymphocyte antigen DRB1, SS1
- Buffer:
- 20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
- Concentration:
- 1 mg/ml
- Extra Details:
- HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Purity:
- >85%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:2798
