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Proteins and Peptides

Human Endostatin Protein (Recombinant)

Product Sizes
100 units
£ POA
LS-G27307-100UNITS
About this Product
SKU:
LS-G27307
Additional Names:
COL18A1, Collagen, type XVIII, alpha 1, Collagen alpha-1(XVIII) chain, Endostatin, KNO, KNO1, KS, Multi-functional protein MFP, Antiangiogenic agent, Collagen alpha 1(xviii), Knobloch syndrome, type 1
Buffer:
Lyophilized with 17 mM citric-phosphate buffer, pH 6.2.
Extra Details:
Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
Physical State:
Lyophilized
Purity:
>97%
Shipping Conditions:
Blue Ice
Storage Conditions:
RT lyophilized. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
LifeSpan Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
  • Manufacturer's Data Sheet:27307
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