Human IGFBP4 Protein (Recombinant His, C-Terminal)
Product Sizes
1 unit
£ POA
LS-G27236-1UNIT
10 units
£ POA
LS-G27236-10UNITS
50 units
£ POA
LS-G27236-50UNITS
About this Product
- SKU:
- LS-G27236
- Additional Names:
- IGFBP4, BP-4, HT29-IGFBP, IGF-binding protein 4, IBP-4, IGFBP-4, IBP4
- Buffer:
- Lyophilized from PBS
- Extra Details:
- Insulin-like growth factor-binding protein 4 (IGF-BP-4), also known as IBP-4, is a secreted glycoprotein belonging to the IGFBP family. IGF-BP-4 is produced by osteoblasts, epidermis, ovarian follicles and other tissues. It binds both insulin-like growth factor (IGF) I and II, and it circulates in the plasma in both glycosylated and non-glycosylated forms. IGF-BP-4 prolongs the half-life of the IGFs and has been shown to inhibit or stimulate the growth-promoting effects of the IGFs. Pregnancy Associated Plasma Protein A (PAPP-A) proteolytically cleaves IGF-BP-4 and reduces its affinity to bind IGFs, and thus serves as an important regulator of IGF-BP-4 function.
- Molecular Weight:
- 30-35 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27236
