Human CXCL4 / PF4 Protein (Recombinant)
Product Sizes
10 units
£ POA
LS-G27122-10UNITS
50 units
£ POA
LS-G27122-50UNITS
About this Product
- SKU:
- LS-G27122
- Additional Names:
- PF4, C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, PF-4, SCYB4, Platelet factor 4
- Buffer:
- Lyophilized from PBS
- Extra Details:
- Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the a-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
- Molecular Weight:
- ~7.8 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27122
