Human HBEGF / HB EGF Protein (Recombinant)
Product Sizes
1 unit
£ POA
LS-G27105-1UNIT
25 units
£ POA
LS-G27105-25UNITS
5 units
£ POA
LS-G27105-5UNITS
About this Product
- SKU:
- LS-G27105
- Additional Names:
- HBEGF, Dtr, DTS, DTSF, HEGFL, Diphtheria Toxin Receptor
- Buffer:
- Lyophilized from PBS
- Extra Details:
- Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.
- Molecular Weight:
- 12-14 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27105
