Mouse IL-1B / IL-1 Beta Protein (Recombinant)
Product Sizes
1 unit
£ POA
LS-G27072-1UNIT
10 units
£ POA
LS-G27072-10UNITS
50 units
£ POA
LS-G27072-50UNITS
About this Product
- SKU:
- LS-G27072
- Additional Names:
- IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta
- Buffer:
- Lyophilized from PBS
- Extra Details:
- Interleukin-1 (IL-1) is a family of cytokines that play a central role in the regulation of immune and inflammatory responses to infections or sterile insults. IL-1a and IL-1Beta are the first two members discovered in this family, which are the products of distinct genes recognizing the same cell surface receptors. IL-1a and IL-1Beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1Beta is interleukin 1Beta-converting enzyme (ICE)/caspase-1. Mature human and mouse IL-1Beta share approximately 75% amino acid sequence identity where human IL-1Beta has been found to be active on murine cell lines. GenScript Interleukin (IL)-1Beta, murine, produced in CHO cells, is a non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17,400 Da.
- Molecular Weight:
- 17.4 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27072
