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Proteins and Peptides

Human FLT3LG / Flt3 Ligand Protein (Recombinant)

Product Sizes
1 unit
£ POA
LS-G27053-1UNIT
10 units
£ POA
LS-G27053-10UNITS
50 units
£ POA
LS-G27053-50UNITS
About this Product
SKU:
LS-G27053
Additional Names:
FLT3LG, FL, Flt3 ligand, FLT3L, SL cytokine
Buffer:
Lyophilized from PBS
Extra Details:
Fms-related tyrosine kinase 3 ligand (Flt3L) is growth factor stimulates the proliferation and differentiation of hematopoietic multipotent progenitors and promotes proliferation of NK cells and dendritic cell subgroups by combination with other growth factors. Flt3L is produced by T cells and stromal fibroblasts, and targeted various cells including hematopoietic stem cells, B cells, T cells, dendritic cells, and NK cells. Flt3L binds to it cognate tyrosine kinase receptor Flt3 and activates JAK/STAT signaling pathway.Flt3L is a hematopoietic four helical bundle cytokine with structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1) demonstrated four conserved cysteines and two glycosylation sites. Flt3L naturally as a non-disulfide-linked homodimer with multiple isoforms. The extracellular portion is approximately 160 amino acid residues in length and the cytoplasmic segment is approximately 20-30 amino acid residues in length.
Molecular Weight:
18~22 kDa (SDS-PAGE)
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
LifeSpan Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
  • Manufacturer's Data Sheet:27053
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