Human CSF1 / MCSF Protein (Recombinant)
Product Sizes
1 unit
£ POA
LS-G27042-1UNIT
10 units
£ POA
LS-G27042-10UNITS
100 units
£ POA
LS-G27042-100UNITS
About this Product
- SKU:
- LS-G27042
- Additional Names:
- CSF1, CSF-1, MCSF, M-CSF, Lanimostim, CSFM
- Buffer:
- 50 mM Tris-HCl, pH 8.0
- Extra Details:
- Macrophage Colony-Stimulating Factor 1 (M-CSF), involved especially in monocytopoiesis, is a hematopoietic growth factor. In mammals, it exits three isoforms, which invariably share an N-terminal 32-aa signal peptide, a 149-residue growth factor domain, a 21-residue transmembrane region and a 37-aa cytoplasmictail. The biological activity of human M-CSF is maintained within the 149-aa growth factor domain, and it is only active in the disulfide-linked dimeric form, which is bonded at Cys63. Recombinant human Macrophage Colony-Stimulating Factor 1 (rhM-CSF) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 159 amino acids each. A fully biologically active molecule, rhM-CSF has a molecular mass of 28 kDaanalyzed by non-reducing SDS-PAGE and is obtained by refolding and chromatographic techniques.
- Molecular Weight:
- 28 kDa (SDS-PAGE)
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles., 2-8[o]C reconstituted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27042
