Human LTA / TNF Beta Protein (Recombinant)
Product Sizes
1 unit
£ POA
LS-G27029-1UNIT
10 units
£ POA
LS-G27029-10UNITS
50 units
£ POA
LS-G27029-50UNITS
About this Product
- SKU:
- LS-G27029
- Additional Names:
- LTA, Lymphotoxin-alpha, LT-alpha, TNFSF1, TNF-beta, TNFB, Tumor necrosis factor beta, LT, TNF Beta
- Buffer:
- Lyophilized from PBS
- Extra Details:
- TNF is secreted by macrophages, monocytes, neutrophils, T-cells, NK-cells following their stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-alpha while CD8 cells secrete little or no TNF-alpha. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL2, GM-CSF. TNF-Beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-Beta is produced by activated T and B lymphocytes, and has similar activities to TNF-a. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. Recombinant Human TNF-Beta produced in E. coli is is a glycosylated polypeptide chain of 172 amino acids. A fully biologically active molecule,rhTNF-Beta has a molecular mass of 18.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
- Molecular Weight:
- 18.6 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27029
