Human CTLA4 Fc Chimera Protein (Recombinant)
Product Sizes
1 unit
£ POA
LS-G27027-1UNIT
50 units
£ POA
LS-G27027-50UNITS
About this Product
- SKU:
- LS-G27027
- Additional Names:
- CTLA-4
- Buffer:
- Lyophilized from Sterile Solution PBS
- Extra Details:
- CTLA-4 is a member of the Ig superfamily, having a single extracellular V-like domain , homology with CD28; The overall sequence homology between CD28 and CTLA-4 is about 20%, but they share a 27%(murine) to 31%(human) identity at the amino acid level. Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. Recombinant Human CTLA-4 Fc Chimera produced in CHO cells is a polypeptide chain containing 359 amino acids with the C-termimal human IgG1 Fc fragment. A fully biologically active molecule, rhCTLA-4 has a molecular mass of 45-48 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
- Molecular Weight:
- 45-48 kDa (SDS-PAGE)
- Physical State:
- Lyophilized
- Purity:
- >98%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:27027
