Human SET / TAF-I Protein (Recombinant His)
Product Sizes
100 ug
£ POA
LS-G2411-100UG
20 ug
£ POA
LS-G2411-20UG
500 ug
£ POA
LS-G2411-500UG
About this Product
- SKU:
- LS-G2411
- Additional Names:
- SET, 2PP2A, HLA-DR-associated protein II, I-2PP2A, TAF-IBETA, SET nuclear oncogene, TAF-I, Template-activating factor I, I2PP2A, IGAAD, IPP2A2, PHAPII, Protein SET
- Buffer:
- 20 mM Tris-HCl, pH 8.0, 0.15 M NaCl, 1 mM DTT, 20% Glycerol
- Concentration:
- 0.5 mg/ml
- Extra Details:
- SET inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. Recombinant human SET protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Purity:
- >90%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:2411
