Human IGLL1 / CD179b Protein (Recombinant His)
Product Sizes
100 ug
£ POA
LS-G2212-100UG
20 ug
£ POA
LS-G2212-20UG
500 ug
£ POA
LS-G2212-500UG
About this Product
- SKU:
- LS-G2212
- Additional Names:
- IGLL1, 14.1, AGM2, CD179b antigen, CD179b, IGO, Lambda5, Ig lambda-5, IGL5, IGLJ14.1, IGL1, IGLL, IGVPB, VPREB2
- Buffer:
- 20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
- Concentration:
- 1 mg/ml
- Extra Details:
- The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human IGLL1protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Purity:
- >85%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:2212
