Human ACE2 / ACE-2 Protein (Recombinant AVI-6His, C-terminus) (Gln18-Ser740)
Product Sizes
20 ug
£ POA
LS-G145897-20UG
About this Product
- SKU:
- LS-G145897
- Additional Names:
- ACE2, ACE-related carboxypeptidase, ACEH, Metalloprotease MPROT15, SARS-CoV2 Coronavirus Receptor, SARS-CoV-2 Coronavirus Receptor, COVID-19 viral receptor
- Buffer:
- Sterile solution in 20 mM Tris-HCl, pH 7.4, 1 mM ZnCl2, 300 mM NaCl, 10% Glycerol
- Extra Details:
- Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
- Molecular Weight:
- 86.2 kDa
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:145897
