Human Complement C5 Protein (Recombinant)
Product Sizes
1 mg
£ POA
LS-G137917-1MG
10 ug
£ POA
LS-G137917-10UG
50 ug
£ POA
LS-G137917-50UG
500 ug
£ POA
LS-G137917-500UG
About this Product
- SKU:
- LS-G137917
- Additional Names:
- C5, Anaphylatoxin C5a analog, CPAMD4, Complement C5, Complement component 5
- Buffer:
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Extra Details:
- Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 a-chain. Human C5a has four a-helices plus three intrachain disulfide bonds that create a triple loop structure. Human C5a is 60% and 54% aa identical to mouse and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2. Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137917
