Human TNNC1 / Cardiac Troponin C Protein (Recombinant 6His, N-terminus)
Product Sizes
1 mg
£ POA
LS-G137911-1MG
10 ug
£ POA
LS-G137911-10UG
50 ug
£ POA
LS-G137911-50UG
500 ug
£ POA
LS-G137911-500UG
About this Product
- SKU:
- LS-G137911
- Additional Names:
- TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, Troponin C, slow, Troponin C1, slow
- Buffer:
- Sterile solution in 20 mM Tris, pH 8.0, 100 mM NaCl, 1 mM DTT, 10% Glycerol
- Extra Details:
- Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93% amino acid sequence identity with mouse and rat cardiac Troponin I.
- Purity:
- >95%
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137911
