Human TMEM173 / STING Protein (Recombinant 6His-SUMO, N-terminus)
Product Sizes
1 mg
£ POA
LS-G137900-1MG
10 ug
£ POA
LS-G137900-10UG
50 ug
£ POA
LS-G137900-50UG
500 ug
£ POA
LS-G137900-500UG
About this Product
- SKU:
- LS-G137900
- Additional Names:
- TMEM173, ERIS, MITA, HSTING, Transmembrane protein 173, HMITA, Mediator of IRF3 activation, MPYS, NET23, STING
- Buffer:
- Sterile solution in PBS, pH 7.4.
- Extra Details:
- Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
- Purity:
- >95%
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137900
