Human IL17RA Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137898-1MG
10 ug
£ POA
LS-G137898-10UG
50 ug
£ POA
LS-G137898-50UG
500 ug
£ POA
LS-G137898-500UG
About this Product
- SKU:
- LS-G137898
- Additional Names:
- IL17RA, CANDF5, CD217 antigen, CDw217, CD217, HIL-17R, IL-17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor, IL-17 receptor A, Interleukin 17 receptor, Interleukin 17 receptor A
- Buffer:
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Extra Details:
- CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to IL17F and binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. It also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. The activation of IL17RA would lead to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6. The signaling events of IL 17 includes activation of NF kappa B and JNK, and require TNF receptor associated factors 6 (TRAF6) in the signaling pathway.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137898
