Mouse F3 / CD142 / Tissue factor Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137887-1MG
10 ug
£ POA
LS-G137887-10UG
50 ug
£ POA
LS-G137887-50UG
500 ug
£ POA
LS-G137887-500UG
About this Product
- SKU:
- LS-G137887
- Additional Names:
- F3, CD142, CD142 antigen, TFA, Tissue factor, Thromboplastin, Coagulation factor III
- Buffer:
- Lyophilized from a sterile solution in 20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.05% Brij-35
- Extra Details:
- Tissue Factor, also known as thromboplastin and CD142, belongs to the tissue factor family which conteins 294 amino acid (aa). Mouse TF consists of a signal peptide (residues 1-28) and the mature chain (residues 29-294). It is a single-pass type I membrane protein that expressed in the liver oscillates in a circadian manner. Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137887
