Mouse PTN / Pleiotrophin Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137885-1MG
10 ug
£ POA
LS-G137885-10UG
50 ug
£ POA
LS-G137885-50UG
500 ug
£ POA
LS-G137885-500UG
About this Product
- SKU:
- LS-G137885
- Additional Names:
- PTN, HARP, HBGF-8, HBNF, HB-GAM, HBBM, HBNF-1, Pleiotrophin, OSF-1, Osteoblast-specific factor 1, HBGF8, HBNF1, NEGF1
- Buffer:
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Extra Details:
- Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson's disease.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137885
