Human ENO1 / Alpha Enolase Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137871-1MG
10 ug
£ POA
LS-G137871-10UG
50 ug
£ POA
LS-G137871-50UG
500 ug
£ POA
LS-G137871-500UG
About this Product
- SKU:
- LS-G137871
- Additional Names:
- ENO1, Alpha Enolase, Alpha enolase like 1, ENO1L1, Enolase 1, MBP-1, MBPB1, MPB1, MYC promoter-binding protein 1, NNE, Phosphopyruvate hydratase, Alpha-enolase, Tau-crystallin, MBP1, MPB-1, C-myc promoter-binding protein, Enolase 1, (alpha), Enolase-alpha, Non-neural enolase, Plasminogen-binding protein, PPH
- Buffer:
- Sterile solution in 20 mM Tris-HCl, pH 7.5, 1 mM MgSO4, 250 mM NaCl, 20% Glycerol
- Extra Details:
- Alpha-enolase, also known as MPB-1, NNE, Enolase 1, belongs to the enolase family. Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding. Isoform MBP-1 interacts with TRAPPC2B. ENO1 interacts with ENO4 and PGAM2. The alpha/alpha homodimer of ENO1 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells. Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses and may also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. ENO1 also stimulates immunoglobulin production.
- Purity:
- >95%
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137871
