Mouse MAG Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137870-1MG
10 ug
£ POA
LS-G137870-10UG
50 ug
£ POA
LS-G137870-50UG
500 ug
£ POA
LS-G137870-500UG
About this Product
- SKU:
- LS-G137870
- Additional Names:
- MAG, GMA, Myelin associated glycoprotein, S-MAG, SIGLEC4A, SIGLEC-4A, Myelin-associated glycoprotein
- Buffer:
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Extra Details:
- Myelin-Associated Glycoprotein (MAG, Siglec-4a), is a type I transmembrane glycoprotein belonging to the Siglec family. It is composed of an extracellular segment containing five Ig-like domains, a single transmembrane segment, and a cytoplasmic domain. Mouse MAG shares 95% and 99% aa sequence identity with human and rat MAG, respectively. MAG functions as an adhesion molecule during neural development. It preferentially binds to alpha -2,3-linked sialic acid terminal structures found on cell surface molecules. MAG is selectively expressed by myelinating oligodendrocytes and Schwann cells and plays an important role in axon-myelin stability. MAG is also reported to regulate the axon cytoskeleton and support the distribution of axon molecules at the nodes of Ranvier. In addition, it has been identified as a major inhibitor of neurite outgrowth.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137870
