Mouse CD6 Protein (Recombinant 6His, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137869-1MG
10 ug
£ POA
LS-G137869-10UG
50 ug
£ POA
LS-G137869-50UG
500 ug
£ POA
LS-G137869-500UG
About this Product
- SKU:
- LS-G137869
- Additional Names:
- CD6, CD6 molecule, T12, TP120, CD6 antigen
- Buffer:
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Extra Details:
- CD6 is a member of the group B scavenger receptor cysteinerich (SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellular SRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a 204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However, the signaling pathways have not been elucidated.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137869
